Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes

Lipid-based vehicles for the oral delivery of poorly water soluble drugs

Andrew Humberstone, William N. Charman · Advanced Drug Delivery Reviews · 1997 · 579 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs

Bok Ki Kang, Jin Soo Lee, Se Kang Chon et al. · International Journal of Pharmaceutics · 2004 · 545 citations

Pharmacy, Pharmaceutics, Pharmacology +16

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

Paul Hadváry, Walter Sidler, Walter Meister et al. · Journal of Biological Chemistry · 1991 · 278 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Susceptibility to Lipase-Mediated Digestion Reduces the Oral Bioavailability of Danazol After Administration as a Medium-Chain Lipid-Based Microemulsion Formulation

Christopher J. H. Porter, Ann Marie Kaukonen, Ben J. Boyd et al. · Pharmaceutical Research · 2004 · 242 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Lipase Activation by Nonionic Detergents

J.A. Hermoso, David Pignol, Brigitte Kerfélec et al. · Journal of Biological Chemistry · 1996 · 232 citations · Full text

Life Sciences, Biochemistry, Catalysis +9