Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Sheng Zhou, John D. Schuetz, Kevin D. Bunting et al. · Nature Medicine · 2001 · 2.3K citations

Life Sciences, Cell Biology, Molecular Biology +7

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

Marc Maliepaard, George L. Scheffer, Ian F. Faneyte et al. · PubMed · 2001 · 1.1K citations

Medicine, Cancer Biology, Oncology +14

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Johan W. Jonker, Marije Buitelaar, Els Wagenaar et al. · Proceedings of the National Academy of Sciences · 2002 · 821 citations · Full text

Medicine, Oncology, Toxicology +14

The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

Partha Krishnamurthy, Douglas D. Ross, Takeo Nakanishi et al. · Journal of Biological Chemistry · 2004 · 653 citations · Full text

Medicine, Cell Biology, Oncology +17

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Yasuyuki Honjo, Christine A. Hrycyna, W Y Medina-Pérez et al. · PubMed · 2001 · 429 citations

Life Sciences, Genetics, Molecular Biology +14