Csilla Hegedüs

Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance

Csilla Hegedüs, Krisztina Truta-Feles, Géza Antalffy et al. · Biochemical Pharmacology · 2012 · 71 citations

Health Sciences, Cancer Drug Resistance, Medicine +10

Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter

Csilla Özvegy‐Laczka, Rozália Laczkó, Csilla Hegedüs et al. · Journal of Biological Chemistry · 2008 · 42 citations · Full text

Immunology, Immunotherapy, Cancer Biology +21

Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter

Ágnes Telbisz, Csilla Hegedüs, Csilla Özvegy‐Laczka et al. · European Journal of Pharmaceutical Sciences · 2011 · 42 citations · Full text

Drug Interactions, Drug Target, Biochemistry +11

Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites

Ágnes Telbisz, Csilla Hegedüs, András Váradi et al. · Drug Metabolism and Disposition · 2014 · 40 citations · Full text

Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter

Zita Gál, Csilla Hegedüs, Gergely Szakács et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2014 · 27 citations

Proteinlipid Interaction, Central Tyrosines, Molecular Physiology +6