Differential survival of AML subpopulations in NOD/SCID mice

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

Hematological Malignancy, Chromatin, Cell Division +10

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Tsvee Lapidot, Christian Sirard, Josef Vormoor et al. · Nature · 1994 · 4.7K citations

Cell Therapy, Transplantation, Marrow Transplantation +11

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

Liqing Jin, Kristin J. Hope, Qiongli Zhai et al. · Nature Medicine · 2006 · 1.2K citations

Hematological Malignancy, Cell Therapy, Medicine +9

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region

Fumihiko Ishikawa, Shuro Yoshida, Yoriko Saito et al. · Nature Biotechnology · 2007 · 966 citations

Regenerative Medicine, Cell Therapy, Medicine +10

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

Liqing Jin, Erwin M. Lee, Hayley S. Ramshaw et al. · Cell stem cell · 2009 · 523 citations · Full text

Hematological Malignancy, Cell Therapy, Immune Cell Development +10