Concepedia

Phosphorylation of HDM2 by Akt

Margaret Ashcroft, Robert L. Ludwig, Douglas Woods, Terry D. Copeland, Hans Weber, Elizabeth J MacRae, Karen H. Vousden

Oncogene · 2002 · 195 citations · 34 references

DOI

Concepts

References

34

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

, , +12

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

Lindsey D. Mayo, David B. Donner · Proceedings of the National Academy of Sciences · 2001 · 1.2K citations · Full text

, , +16

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

Francesca J. Stott, Stewart Bates, Marion C. James et al. · The EMBO Journal · 1998 · 1.2K citations · Full text

, , +9

Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53

Shengyun Fang, Jane P. Jensen, Robert L. Ludwig et al. · Journal of Biological Chemistry · 2000 · 1K citations · Full text

, , +15

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

Binhua P. Zhou, Yong Liao, Weiya Xia et al. · Nature Cell Biology · 2001 · 940 citations

, , +10