Concepedia

Activators of the Rat Pregnane X Receptor Differentially Modulate Hepatic and Intestinal Gene Expression

Dylan P. Hartley, Xudong Dai, Yudong D. He, Edward J. Carlini, Bonnie Wang, Su-Er W. Huskey, Roger G. Ulrich, Thomas H. Rushmore, Raymond Evers, David C. Evans

Molecular Pharmacology · 2004 · 77 citations · 46 references

DOI

Concepts

References

46

Functional Discovery via a Compendium of Expression Profiles

Timothy R. Hughes, Matthew J. Marton, Roland Stoughton et al. · Cell · 2000 · 2.6K citations · Full text

, , +14

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell · 1998 · 1.5K citations · Full text

, , +16

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

Timothy R. Hughes, Mao Mao, Allan R. Jones et al. · Nature Biotechnology · 2001 · 1.3K citations

, , +11

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

Frances M. Sladek, Weimin Zhong, Edmund Lai et al. · Genes & Development · 1990 · 1.1K citations · Full text

, , +10