Concepedia

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

Chiara Zuccato, Daniel Liber, Catarina Ramos, Alessia Tarditi, Dorotea Rigamonti, Marzia Tartari, Marta Valenza, Elena Cattaneo

Pharmacological Research · 2005 · 194 citations · 39 references

DOI

Concepts

References

39

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

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Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

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Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear Inclusions

Frédéric Saudou, Steven Finkbeiner, Didier Devys et al. · Cell · 1998 · 1.6K citations · Full text

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Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Chiara Zuccato, Andrea Ciammola, Dorotea Rigamonti et al. · Science · 2001 · 1.3K citations

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