Concepedia

BMD188, A novel hydroxamic acid compound, demonstrates potent anti-prostate cancer effectsin vitro andin vivo by inducing apoptosis: requirements for mitochondria, reactive oxygen species, and proteases

Dean G. Tang, Li Li, Zhenyu Zhu, Bindu Joshi, Lawrence J. Marnett, Kenneth V. Honn, John D. Crissman, S Krajewski, John C. Reed, Arthur T. Porter

Pathology & Oncology Research · 1998 · 21 citations · 36 references

DOI

Concepts

References

36

Mitochondrial control of nuclear apoptosis.

Naoufal Zamzami, Santos A. Susín, Philippe Marchetti et al. · The Journal of Experimental Medicine · 1996 · 1.4K citations · Full text

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Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

Yutaka Eguchi, S Shimizu, Yoshihide Tsujimoto · PubMed · 1997 · 1.3K citations

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Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

Klaus Schulze‐Osthoff, Annette Bakker, Bart Vanhaesebroeck et al. · Journal of Biological Chemistry · 1992 · 940 citations · Full text

, , +15

An essential role for free radicals and derived species in signal transduction

Harry M. Lander · The FASEB Journal · 1997 · 901 citations

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Mitochondrial permeability transition is a central coordinating event of apoptosis.

Philippe Marchetti, M Castedo, Santos A. Susín et al. · The Journal of Experimental Medicine · 1996 · 855 citations · Full text

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