Concepedia

Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivatives

Vivek Kumar, Nidhi Rani, P. Aggarwal, Vinod K. Sanna, Anu Singh, Manu Jaggi, Narendra Joshi, Pramod Kumar Sharma, Raghuveer Irchhaiya, Anand C. Burman

Bioorganic & Medicinal Chemistry Letters · 2008 · 70 citations · 12 references

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References

12

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

Emily Pisha, Heebyung Chai, Ik‐Soo Lee et al. · Nature Medicine · 1995 · 886 citations

, , +14

Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid

Simone Fulda, Carsten Scaffidi, Santos A. Susín et al. · Journal of Biological Chemistry · 1998 · 374 citations · Full text

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Synthesis of A-Seco Derivatives of Betulinic Acid with Cytotoxic Activity

Milan Urban, Jan Šarek, Jiří Klinot et al. · Journal of Natural Products · 2004 · 128 citations

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Betulinic Acid Derivatives:  A New Class of Human Immunodeficiency Virus Type 1 Specific Inhibitors with a New Mode of Action

Michel Evers, Christèle Poujade, Françoise Soler et al. · Journal of Medicinal Chemistry · 1996 · 124 citations

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