α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection

CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

Jason M. Brenchley, Timothy W. Schacker, Laura E. Ruff et al. · The Journal of Experimental Medicine · 2004 · 1.8K citations · Full text

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

C Berlin, Ellen L. Berg, Michael Briskin et al. · Cell · 1993 · 1.4K citations

Inflammation, α4β7 Integrin Mediates, Molecular Immunology +9

Gastrointestinal Tract as a Major Site of CD4 ⁺ T Cell Depletion and Viral Replication in SIV Infection

Ronald S. Veazey, MaryAnn DeMaria, Laura V. Chalifoux et al. · Science · 1998 · 1.4K citations

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Joseph J. Mattapallil, Daniel C. Douek, Brenna J. Hill et al. · Nature · 2005 · 1.3K citations

Viral Persistence, Multiple Tissues, Human Retrovirus +5

HIV preferentially infects HIV-specific CD4+ T cells

Daniel C. Douek, Jason M. Brenchley, Michael R. Betts et al. · Nature · 2002 · 1.3K citations

Human Retrovirus, Immunology, Antiviral Response +3