Towards a vaccine for rheumatic fever: identification of a conserved target epitope on M protein of group A streptococci

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Richard A. Houghten · Proceedings of the National Academy of Sciences · 1985 · 1.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Resurgence of Acute Rheumatic Fever in the Intermountain Area of the United States

L. George Veasy, S E Wiedmeier, Garth S. Orsmond et al. · New England Journal of Medicine · 1987 · 696 citations

Public Health, Infectious Diseases, Pediatrics +11

Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.

Richard J. Rodeheffer, Gary Gerstenblith, Lewis C. Becker et al. · Circulation · 1984 · 660 citations · Full text

Education, Cardiology, Physiology +17

Complete nucleotide sequence of type 6 M protein of the group A Streptococcus. Repetitive structure and membrane anchor.

Susan K. Hollingshead, V A Fischetti, June R. Scott · Journal of Biological Chemistry · 1986 · 361 citations · Full text

Life Sciences, Microbiology, Molecular Biology +14

DIFFERENTIATION OF GROUP A STREPTOCOCCI WITH A COMMON R ANTIGEN INTO THREE SEROLOGICAL TYPES, WITH SPECIAL REFERENCE TO THE BACTERICIDAL TEST

Rebecca C. Lancefield · The Journal of Experimental Medicine · 1957 · 289 citations · Full text

Life Sciences, Microbiology, Bacteriology +9