T- and B-Cell Nonresponsiveness to Self-αB-Crystallin in SJL Mice Prevents the Induction of Experimental Allergic Encephalomyelitis

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

Jody L. Baron, Joseph A. Madri, Nancy H. Ruddle et al. · The Journal of Experimental Medicine · 1993 · 830 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

Juan J. Lafaille, Fabienne Van de Keere, Albert Hsu et al. · The Journal of Experimental Medicine · 1997 · 429 citations · Full text

Life Sciences, Immunology, Pathology +17

The small heat-shock protein αB-crystallin as candidate autoantigen in multiple sclerosis

Johannes M. van Noort, Arianne C. van Sechel, Jeffrey J. Bajramović et al. · Nature · 1995 · 402 citations

Life Sciences, Molecular Biology, Neurology +16

Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype

Dale Ando, Julie Clayton, Dwight H. Kono et al. · Cellular Immunology · 1989 · 392 citations

Life Sciences, Immunology, Neuroscience +16

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells

Ludger Klein, Matthias Klugmann, Klaus-Armin Nave et al. · Nature Medicine · 2000 · 391 citations

Life Sciences, Immunology, Molecular Biology +17