Concepedia

Publication | Open Access

The Oncogenic Effect of Sulfatase 2 in Human Hepatocellular Carcinoma Is Mediated in Part by Glypican 3–Dependent Wnt Activation

DOIFull Paper Access

116

Citations

19

References

2010

Year

Jin-Ping Lai, Abdul M. Oseini, Catherine D. Moser, Chunrong Yu, Sherine F. Elsawa, Chunling Hu, Ikuo Nakamura, Tao Han, Ileana Aderca, Hajime Isomoto,
Hepatology

Abstract

Together, these findings identify a novel mechanism mediating the oncogenic function of SULF2 in HCC that includes GPC3-mediated activation of Wnt signaling via the Wnt3a/glycogen synthase kinase 3 beta axis.

References

YearCitations

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