Concepedia

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

Wenyi Wei, Nagi G. Ayad, Yong Wan, Guo-Jun Zhang, Marc W. Kirschner, William G. Kaelin

Nature · 2004 · 499 citations · 23 references

DOI

Concepts

References

23

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

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Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis

Thomas J. McGarry, Marc W. Kirschner · Cell · 1998 · 896 citations · Full text

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The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

Cathie M. Pfleger, Marc W. Kirschner · Genes & Development · 2000 · 731 citations · Full text

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Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication

Kei Nakayama · The EMBO Journal · 2000 · 710 citations · Full text

, , +16

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

Hedwig Sutterlüty, Eric Chatelain, Alain Marti et al. · Nature Cell Biology · 1999 · 699 citations

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