Concepedia

Discovery of dipiperidines as new antitubercular agents

Elena Bogatcheva, Colleen F. Hanrahan, Ping Chen, Jacqueline Gearhart, Katherine A. Sacksteder, Leo Einck, Carol A. Nacy, Marina Protopopova

Bioorganic & Medicinal Chemistry Letters · 2009 · 39 citations · 8 references

DOI

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References

8

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines

Marina Protopopova, Colleen F. Hanrahan, B. V. Nikonenko et al. · Journal of Antimicrobial Chemotherapy · 2005 · 371 citations · Full text

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Pharmacodynamics and pharmacokinetics of SQ109, a new diamine‐based antitubercular drug

Lee Jia, Joseph E. Tomaszewski, Colleen F. Hanrahan et al. · British Journal of Pharmacology · 2004 · 235 citations · Full text

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Combinatorial Lead Optimization of [1,2]-Diamines Based on Ethambutol as Potential Antituberculosis Preclinical Candidates

Richard Lee, Marina Protopopova, Emma T. Crooks et al. · Journal of Combinatorial Chemistry · 2003 · 208 citations

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Drug Therapy of Experimental Tuberculosis (TB): Improved Outcome by Combining SQ109, a New Diamine Antibiotic, with Existing TB Drugs

B. V. Nikonenko, Marina Protopopova, Rowena Samala et al. · Antimicrobial Agents and Chemotherapy · 2007 · 144 citations · Full text

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Identification of New Diamine Scaffolds with Activity against <i>Mycobacterium tuberculosis</i>

Elena Bogatcheva, Colleen F. Hanrahan, B. V. Nikonenko et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

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