Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis

Xing‐Jie Liang, Huan Meng, Yingze Wang, +14

Proceedings of the National Academy of Sciences

Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

Shivaani Kummar, Alice P. Chen, Jiuping Ji, +19

Cancer Research

Pharmacodynamics and pharmacokinetics of SQ109, a new diamine‐based antitubercular drug

Lee Jia, Joseph E. Tomaszewski, Colleen F. Hanrahan, +5

British Journal of Pharmacology

Pharmaceutical ScienceHigh-throughput Combinatorial ScreeningTuberculosis PreventionImmunologyPharmacotherapy +16

Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer

Huifang Nie, Xiaodong Xie, Doudou Zhang, +8

Nanoscale

Polynitrosylated proteins: characterization, bioactivity, and functional consequences.

Daniel I. Simon, Mark E. Mullins, Lee Jia, +3

Proceedings of the National Academy of Sciences

Protein ChemistryProtein FunctionBiochemistryReactive Nitrogen SpecieNitric Oxide +11

EpCAM aptamer-functionalized mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery

Xiaodong Xie, Fengqiao Li, Huijuan Zhang, +5

European Journal of Pharmaceutical Sciences

NanoparticlesNanomedicineEngineeringNano-drug DeliveryTumor Targeting +2

Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer

Fengqiao Li, Hao Mei, Yu Gao, +5

Biomaterials

Hypoxia-induced Drug ResistanceAptamer-modified Liposomal ComplexesPolymer-drug ConjugateMedicineTumor Targeting +4

Nanoparticle Formulation Increases Oral Bioavailability of Poorly Soluble Drugs: Approaches, Experimental Evidences and Theory

Lee Jia

Current Nanoscience

Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in Bad and hypophosphorylated retinoblastoma expressions

Chye Sun Ong, Evelyn Tran, Tuong Nguyen, +5

Oncology Reports

Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release

Shu Lian, Ruizhi Xie, Yuying Ye, +7

EBioMedicine