Concepedia

Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection

Maritza Jaramillo, María Adelaida Gómez, Ola Larsson, Marina Tiemi Shio, Ivan Topisirović, Irazú Contreras, Randi Luxenburg, Amy Rosenfeld, Rodney Colina, Robert McMaster,

Cell Host & Microbe · 2011 · 174 citations · 40 references

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40

Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

Kenta Hara, Yoshiko Maruki, K. Yoshino et al. · Cell · 2002 · 1.8K citations · Full text

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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

Arnim Pause, Graham J. Belsham, Anne‐Claude Gingras et al. · Nature · 1994 · 1.2K citations

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Hierarchical phosphorylation of the translation inhibitor 4E-BP1

Anne‐Claude Gingras, Brian Raught, Steven P. Gygi et al. · Genes & Development · 2001 · 884 citations · Full text

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mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

Ryan J.O. Dowling, Ivan Topisirović, Tommy Alain et al. · Science · 2010 · 755 citations

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Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation.

Laura Beretta, Anne‐Claude Gingras, Yuri V. Svitkin et al. · The EMBO Journal · 1996 · 673 citations · Full text

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