Concepedia

Inhibition of Vascular Smooth Muscle Cell Proliferation and Neointimal Accumulation by Adenovirus-Mediated Gene Transfer of Cytosine Deaminase

Robert L. Harrell, M. A. Sharmini Rajanayagam, A. Masharn Doanes, Raul J. Guzman, Edward A. Hirschowitz, Ronald G. Crystal, Stephen E. Epstein, Toren Finkel

Circulation · 1997 · 60 citations · 20 references

DOI

Abstract

Our results suggest that adenovirus-mediated gene transfer of CD along with 5-FC administration may be a useful strategy to treat the proliferative aspects of restenosis.

References

20

Significance of quiescent smooth muscle migration in the injured rat carotid artery.

A W Clowes, Stephen M. Schwartz · Circulation Research · 1985 · 571 citations · Full text

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Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system.

Craig A. Mullen, Mogens Kilstrup, R. Michael Blaese · Proceedings of the National Academy of Sciences · 1992 · 504 citations · Full text

, , +17

Cytostatic Gene Therapy for Vascular Proliferative Disorders with a Constitutively Active form of the Retinoblastoma Gene Product

Mark W. Chang, Eliav Barr, Jonathan Seltzer et al. · Science · 1995 · 448 citations

, , +18

Gene Therapy for Vascular Smooth Muscle Cell Proliferation After Arterial Injury

Takeshi Ohno, David J. Gordon, Hong San et al. · Science · 1994 · 439 citations

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<i>In Vitro</i> Evidence That Metabolic Cooperation Is Responsible for the Bystander Effect Observed with HSV <i>tk</i> Retroviral Gene Therapy

Wan Li Bi, Linda M. Parysek, Ronald E. Warnick et al. · Human Gene Therapy · 1993 · 420 citations