Concepedia

Mycalamide D, a New Cytotoxic Amide from the New Zealand Marine Sponge <i>Mycale</i> Species

Lyndon M. West, Peter T. Northcote, Kylie Hood, John H. Miller, Michael J. Page

Journal of Natural Products · 2000 · 57 citations · 8 references

DOI

Concepts

Abstract

A new mycalamide, mycalamide D (3), has been isolated from the New Zealand marine sponge Mycale sp. This new metabolite, in which the C13-O-methyl group of mycalamide A (1) is replaced by a hydrogen atom, was found to be cytotoxic to a range of mammalian cell lines, with a potency approximately 20-fold less than that of 1.

References

8

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Isolation and structure elucidation of onnamide A, a new bioactive metabolite of a marine sponge, Theonella sp

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Chang Yong Hong, Yoshito Kishi · Journal of the American Chemical Society · 1991 · 83 citations

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