Frequency of CYP2C9 and VKORC1 Gene Polymorphisms and Their Influence on Warfarin Dose in Egyptian Pediatric Patients

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

J. A. Johnson, Li Gong, Michelle Whirl‐Carrillo et al. · Clinical Pharmacology & Therapeutics · 2011 · 648 citations

Medicine, Pharmacology, Pharmacotherapy +17

Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (<i>DPYD</i>) in the Egyptian population

Samar Hamdy, Masahiro Hiratsuka, Kaori Narahara et al. · British Journal of Clinical Pharmacology · 2002 · 153 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Developmental changes in pharmacokinetics and pharmacodynamics of warfarin enantiomers in Japanese children

Hakuo Takahashi · Clinical Pharmacology & Therapeutics · 2000 · 131 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Liver volume as a determinant of drug clearance in children and adolescents.

Daryl J. Murry, W R Crom, Wilburn E. Reddick et al. · Drug Metabolism and Disposition · 1995 · 121 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

VKORC1 and CYP2C9 genotype and patient characteristics explain a large proportion of the variability in warfarin dose requirement among children

Tina Biss, Peter Avery, Leonardo R. Brandão et al. · Blood · 2011 · 107 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +12