In vitro and in vivo gene-transferring characteristics of novel cationic lipids, DMKD (O,O'-dimyristyl-N-lysyl aspartate) and DMKE (O,O'-dimyristyl-N-lysyl glutamate)

A novel cationic liposome reagent for efficient transfection of mammalian cells

Xiang Gao, Leaf Huang · Biochemical and Biophysical Research Communications · 1991 · 845 citations

Pharmacy, Biotechnology, Pharmaceutics +16

In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes

S Li, Leaf Huang · Gene Therapy · 1997 · 473 citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +14

Characterization of Cationic Liposome-Mediated Gene Transfer <i>In Vivo</i> by Intravenous Administration

Young Song, Feng Liu, Shaoyou Chu et al. · Human Gene Therapy · 1997 · 298 citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +17

A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung.

Christopher J. Wheeler, Philip L. Felgner, Ya-Li Tsai et al. · Proceedings of the National Academy of Sciences · 1996 · 279 citations · Full text

Pharmacy, Molecular Biology, Pharmaceutics +17

Inclusion of the Hepatic Locus Control Region, an Intron, and Untranslated Region Increases and Stabilizes Hepatic Factor IX Gene Expression in Vivo but Not in Vitro

Carol H. Miao, Kazuo Ohashi, G. Patijn et al. · Molecular Therapy · 2000 · 245 citations · Full text

Life Sciences, Genetics, Molecular Biology +14