Concepedia

Rapid Aggregate Formation of the Huntingtin N-Terminal Fragment Carrying an Expanded Polyglutamine Tract

Noriko Hazeki, Koichiro Nakamura, Jun Goto, Ichiro Kanazawa

Biochemical and Biophysical Research Communications · 1999 · 34 citations · 31 references

DOI

Concepts

References

31

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

, , +17

Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear Inclusions

Frédéric Saudou, Steven Finkbeiner, Didier Devys et al. · Cell · 1998 · 1.6K citations · Full text

, , +12

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

Eberhard Scherzinger, Rudi Lurz, Mark Turmaine et al. · Cell · 1997 · 1.3K citations · Full text

, , +10

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.

M. F. Perutz, T. Johnson, Masashi Suzuki et al. · Proceedings of the National Academy of Sciences · 1994 · 1.1K citations

, , +17