Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Margherita Maffei, Jeffrey L. Halaas, Éric Ravussin et al. · Nature Medicine · 1995 · 3.7K citations

Medicine, Endocrinology, Physiology +15

Narcolepsy in orexin Knockout Mice

Richard M. Chemelli, Jon T. Willie, Christopher M. Sinton et al. · Cell · 1999 · 3.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Medicine, Medicinal Chemistry, Pharmacology +10

Apelin, a Newly Identified Adipokine Up-Regulated by Insulin and Obesity

Jérémie Boucher, Bernard Masri, Danièle Daviaud et al. · Endocrinology · 2005 · 886 citations

Life Sciences, Cell Biology, Molecular Biology +15

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Kazuhiko Tatemoto, Kiyoshige Takayama, Iku Kumaki et al. · Regulatory Peptides · 2001 · 643 citations

Medicine, Cardiology, Physiology +14