Isolation and Purification of Protein Granules from Escherichia coli Cells Overproducing Bovine Growth Hormone

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

A low-viscosity epoxy resin embedding medium for electron microscopy

Arthur R. Spurr · Journal of Ultrastructure Research · 1969 · 12.9K citations

Engineering, Materials Engineering, Materials Science +5

Expression in <i>Escherichia coli</i> of a Chemically Synthesized Gene for the Hormone Somatostatin

Keiichi Itakura, Tadaaki Hirose, Roberto Crea et al. · Science · 1977 · 851 citations

Life Sciences, Biochemistry, Molecular Biology +17

Cloned Viral Protein Vaccine for Foot-and-Mouth Disease: Responses in Cattle and Swine

Dennis G. Kleid, Daniel G. Yansura, Barbara Small et al. · Science · 1981 · 500 citations

Life Sciences, Biotechnology, Immunology +17

Cytoplasmic Inclusion Bodies in <i>Escherichia coli</i> Producing Biosynthetic Human Insulin Proteins

Daniel C. Williams, Richard M. Van Frank, William L. Muth et al. · Science · 1982 · 312 citations

Life Sciences, Biochemistry, Molecular Biology +16