Roberto Crea

A system for shotgun DNA sequencing

Joachim Messing, Roberto Crea, Peter H. Seeburg · Nucleic Acids Research · 1981 · 2.6K citations · Full text

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.

James S. Huston, Dennis J. Levinson, M Mudgett-Hunter et al. · Proceedings of the National Academy of Sciences · 1988 · 1.6K citations · Full text

E. Coli, Specific Activity, Molecular Biology +18

Expression in Escherichia coli of chemically synthesized genes for human insulin.

David V. Goeddel, Dennis G. Kleid, Francisco Bolívar et al. · Proceedings of the National Academy of Sciences · 1979 · 852 citations · Full text

Engineering, Insulin Peptides, Glycobiology +18

Expression in <i>Escherichia coli</i> of a Chemically Synthesized Gene for the Hormone Somatostatin

Keiichi Itakura, Tadaaki Hirose, Roberto Crea et al. · Science · 1977 · 845 citations

Bioorganic Chemistry, Engineering, Peptide Engineering +19

Human leukocyte interferon produced by E. coli is biologically active

David V. Goeddel, Elizabeth Yelverton, Axel Ullrich et al. · Nature · 1980 · 529 citations

Inflammation, Cytokine, E. Coli +8