Prostaglandins in Human Burn Blister Fluid

Abstract

Abstract Acidic lipids with smooth muscle stimulating activity were isolated from human burn blister fluid. Analysis by silicic acid chromatography and thin‐layer chromatography indicated the presence of prostaglandin E and F compounds. Prostaglandin E 2 (about 1.9 ng/ml of blister fluid) was identified and quantitatively determined by gas‐liquid chromatography—mass spectrometry. No metabolic conversion of tritium‐labelled prostaglandin E 1 incubated with blister fluid was observed.