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A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

Aude Dupré, Louise Boyer-Châtenet, Rose M Sattler, Ami P. Modi, Ji‐Hoon Lee, Matthew L Nicolette, Levy Kopelovich, Maria Jasin, Richard Baer, Tanya T. Paull,

Nature Chemical Biology · 2008 · 409 citations · 30 references

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30

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

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Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

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ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Ji‐Hoon Lee, Tanya T. Paull · Science · 2005 · 1.4K citations

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

Andrew J. Pierce, Roger D. Johnson, L.H. Thompson et al. · Genes & Development · 1999 · 1.4K citations · Full text

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A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

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