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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

Molecular PharmacologyMedicinal ChemistryDrug TargetBiochemistryMedicineNatural SciencesMechanism Of ActionCytochrome P450PharmacotherapyPharmacologyPharmaceutical ChemistryDrug DiscoveryPart IiDiamine Inhibitors