Luong Tsai

Clinical targeting of HIV capsid protein with a long-acting small molecule

John O. Link, Martin S. Rhee, Winston C. Tse et al. · Nature · 2020 · 392 citations · Full text

Natural Sciences, Human Retrovirus, Immunology +10

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Manuel Tsiang, G.S. Jones, Joshua Goldsmith et al. · Antimicrobial Agents and Chemotherapy · 2016 · 274 citations · Full text

Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer

Lianhong Xu, Hongtao Liu, Bernard P. Murray et al. · ACS Medicinal Chemistry Letters · 2010 · 200 citations

Human Cyp3a, Pharmacotherapy, Antiviral Drug +19

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

Ke Peng, Walter Muranyi, Bärbel Glass et al. · eLife · 2014 · 164 citations · Full text

Viral Replication, Immunology, Viral Capsid +18

Non-Catalytic Site HIV-1 Integrase Inhibitors Disrupt Core Maturation and Induce a Reverse Transcription Block in Target Cells

M. Balakrishnan, Stephen R. Yant, Luong Tsai et al. · PLoS ONE · 2013 · 125 citations · Full text

Hiv-1 Integrase, Hiv-1 Core Maturation, Viral Replication +19