Concepedia

Melody S. Lee

MS

Statistics

Publications

6

Citations

322

H-Index

6

Active since

2010

Affiliations

Gilead Sciences (United States)(Current)

University of California, San Francisco

Melody S. Lee is an author at Gilead Sciences (United States) specializing in enzyme inhibition, drug discovery, and drug design.

Publications per year

2010–2017

6

Publications

6

Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer

Lianhong Xu, Hongtao Liu, Bernard P. Murray et al. · ACS Medicinal Chemistry Letters · 2010 · 200 citations

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A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies

Eric L. Schneider, Melody S. Lee, Aida Baharuddin et al. · Journal of Molecular Biology · 2011 · 49 citations

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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

Lianhong Xu, Hongtao Liu, Allen Y. Hong et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 26 citations · Full text

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Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms

D. Wilkinson, Angela Kate Habgood, Heather K. Lamb et al. · Arthritis & Rheumatology · 2017 · 21 citations · Full text

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Discovery of GS-8374, a potent human immunodeficiency virus type 1 protease inhibitor with a superior resistance profile

Gong-Xing He, Zhengyu Yang, Matthew A. Williams et al. · MedChemComm · 2011 · 15 citations

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