Interleukin-10 protects the ischemic heart from reperfusion injury via the STAT3 pathway

Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization

Jochen Schust, Bianca Sperl, Angela Hollis et al. · Chemistry & Biology · 2006 · 1.1K citations

Life Sciences, Medicinal Chemistry, Molecular Biology +11

Tumor necrosis factor-alpha and interleukin-1 beta synergistically depress human myocardial function

Brian S. Cain, Daniel R. Meldrum, Charles A. Dinarello et al. · Critical Care Medicine · 1999 · 423 citations

Veterinary Medicine, Cardiology, Immunology +17

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR

Prasanna Krishnamurthy, Johnson Rajasingh, Erin Lambers et al. · Circulation Research · 2008 · 421 citations · Full text

Life Sciences, Cardiology, Immunology +17

Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization

Hani A. Hennein, Hailu Ebba, Jorge L. Rodríguez et al. · Journal of Thoracic and Cardiovascular Surgery · 1994 · 413 citations · Full text

Medicine, Cardiology, Immunology +16

Signal Transducer and Activator of Transcription 3 Is the Dominant Mediator of the Anti-Inflammatory Effects of IL-10 in Human Macrophages

Lynn Williams, Laura Bradley, Alexandra Smith et al. · The Journal of Immunology · 2004 · 388 citations · Full text

Life Sciences, Immunology, Pathology +17