Concepedia

Gamma/delta T cells are the predominant source of interleukin‐17 in affected joints in collagen‐induced arthritis, but not in rheumatoid arthritis

Yoshinaga Ito, Takashi Usui, Shio Kobayashi, Mikiko Iguchi-Hashimoto, Hiromu Ito, Hiroyuki Yoshitomi, Takashi Nakamura, Masakazu Shimizu, Daisuke Kawabata, Naoichiro Yukawa,

Arthritis & Rheumatism · 2009 · 158 citations · 46 references

DOI

Abstract

Gamma/delta T cells were antigen independently stimulated by inflammation at affected joints and produced enhanced amounts of IL-17 to exacerbate arthritis in mice with CIA but not in SKG mice with arthritis or patients with RA.

References

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