PubMed · 2003 · 13 citations · 52 references
MedicineDermatologyInfectious DiseasesDermatopathologyHistopathologyInfectious Disease PathologyGranulomatous DermatitisGranulomatous DermatosesInfectious DermatosesInflammatory DermatosesParasitic InfectionsSkin InfectionsGranulomatous LesionsGranulomatous ReactionsHistopathologic ExaminationHistopathologic Patterns Of InfectionHistoplasmosis LesionsInfectious Disease HistopathologyLesion HistopathologySkin Infection Treatment
Histoplasmosis is usually a lung infection due to Histoplasma capsulatum var Capsulatum. Skin lesions are present in 10 to 17% of cases and it appears to have higher prevalence in Mexico. We report on three cases, all males with AIDS, of 26, 33 and 44 years of age. They presented fever, lymphadenopathy and weight loss. One had lingual ulcer and the other two, disseminated erythemato-violaceus plaques, papular and fistular lesions. The histopathologic study showed granulomatous lesions and Histoplasma capsulatum was isolated in cultures. All patients were treated successfully with amphotericin B with a total of 1.5 gm accumulative dose. Clinical skin lesions of histoplasmosis and good response to treatment are discussed.
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