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Antilipid Peroxidative Property of Shilajit
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1996
Year
Lipid PeroxidationGlutathione ContentCumene HydroperoxideRedox BiologyOxidative StressRat Liver HomogenateToxicologyHepatotoxicityAntilipid Peroxidative PropertyHealth SciencesBiochemistryLiver PhysiologyReactive Oxygen SpecieMetabolomicsPharmacologyDrug-induced Liver InjuryPhysiologyMetabolismMedicine
We have investigated the effect of shilajit on lipid peroxidation and glutathione content in rat liver homogenate. It inhibited lipid peroxidation induced by cumene hydroperoxide and ADP/Fe++ complex in a dose dependent manner. It also reduced the rate of oxidation of reduced glutathione content and inhibited ongoing lipid peroxidation, induced by these agents immediately after its addition to the incubation system.