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The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignMicrotubule InhibitorsBiological EvaluationAnti-cancer AgentPotential Antitumor AgentsPharmacologyPharmaceutical ChemistryDrug Discovery