Concepedia

SV2A protein is a broad-spectrum anticonvulsant target: Functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy

Rafał M. Kamiński, Alain Matagne, Karine Leclercq, Michel Gillard, Philippe Michel, Benoît Kenda, Patrice Talaga, Henrik Klitgaard

Neuropharmacology · 2007 · 168 citations · 35 references

DOI

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References

35

Biostatistical Analysis

William H. Baltosser, Jerrold H. Zar · Ecology · 1996 · 35.5K citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

Ronald J. Racine · Electroencephalography and Clinical Neurophysiology · 1972 · 7.2K citations

, , +16

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

Berkley A. Lynch, Nathalie Lambeng, Karl Nocka et al. · Proceedings of the National Academy of Sciences · 2004 · 1.6K citations · Full text

, , +17

Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy

Henrik Klitgaard, Alain Matagne, J.G. Gobert et al. · European Journal of Pharmacology · 1998 · 509 citations

, , +12

Multicenter Double‐Blind, Randomized, Placebo‐Controlled Trial of Levetiracetam as Add‐On Therapy in Patients with Refractory Partial Seizures

Simon Shorvon, Armand Löwenthal, Diéter Janz et al. · Epilepsia · 2000 · 448 citations

, , +15