(1S,2R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizine (swainsonine), an α-mannosidase inhibitor from Rhizoctonia leguminicola

Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II.

Daulat R.P. Tulsiani, Thomas M. Harris, Oscar Touster · Journal of Biological Chemistry · 1982 · 464 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A Spectroscopic Investigation of Swainsonine: An α-Mannosidase Inhibitor Isolated from <i>Swainsona canescens</i>

SM Colegate, PR Dorling, CR Huxtable · Australian Journal of Chemistry · 1979 · 425 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Loco Intoxication: Indolizidine Alkaloids of Spotted Locoweed ( <i>Astragalus lentiginosus</i> )

Russell J. Molyneux, Lynn F. James · Science · 1982 · 413 citations

Life Sciences, Botany, Pharmacology +11

Castanospermine, A 1,6,7,8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe

Liza D. Hohenschutz, E.Arthur Bell, Phillip J. Jewess et al. · Phytochemistry · 1981 · 374 citations

Life Sciences, Botany, Plant Sciences +11

Inhibition of lysosomal α-mannosidase by swainsonine, an indolizidine alkaloid isolated from <i>Swainsona canescens</i>

P. R. Dorling, C. R. Huxtable, Steven M. Colegate · Biochemical Journal · 1980 · 372 citations · Full text

Life Sciences, Biochemistry, Pharmacology +9