A Spectroscopic Investigation of Swainsonine: An α-Mannosidase Inhibitor Isolated from <i>Swainsona canescens</i>

Abstract

A potent inhibitor of a-mannosidase was isolated from Swainsona canescens . The inhibitor was shown to be an indolizidinetriol by spectroscopic techniques and the relative stereochemistry was defined as 8aß-indolizidine-la,2a,8ß-triol.