Concepedia

Age-related accumulation of oxidative DNA damage and alterations in levels of p16INK4a/CDKN2a, p21WAF1/CIP1/SDI1 and p27KIP1 in human CD4+ T cell clones in vitro

Paul Hyland, Christopher R. Barnett, Graham Pawelec, Yvonne Barnett

Mechanisms of Ageing and Development · 2001 · 43 citations · 53 references

DOI

Concepts

References

53

A simple technique for quantitation of low levels of DNA damage in individual cells

Narendra P. Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research · 1988 · 10.8K citations · Full text

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The serial cultivation of human diploid cell strains

Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.4K citations

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WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

, , +13

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

, , +13

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14