A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals

Direct oxidation of tertiary allylic alcohols. A simple and effective method for alkylative carbonyl transposition

William G. Dauben, Drake M. Michno · The Journal of Organic Chemistry · 1977 · 316 citations

Natural Sciences, Chemistry, Catalysis +10

Desulfonylation of aryl alkyl sulfones

Barry M. Trost, Henry C. Arndt, Paul E. Strege et al. · Tetrahedron Letters · 1976 · 284 citations

Natural Sciences, Chemistry, Medicinal Chemistry +3

Tosylhydrazones. V. Reaction of Tosylhydrazones with Alkyllithium Reagents. A New Olefin Synthesis.

Robert H. Shapiro, Marsha J. Heath · Journal of the American Chemical Society · 1967 · 233 citations

Natural Sciences, Chemistry, Carbohydrate Chemistry +6

Total synthesis of leukotriene B5

E. J. Corey, Stephen G. Pyne, Wei-guo Su · Tetrahedron Letters · 1983 · 125 citations

Natural Sciences, Chemistry, Pharmacology +8

Selective deprotection of alcoholic and phenolic silyl ethers

E. W. COLLINGTON, Harry Finch, Ian J. Smith · Tetrahedron Letters · 1985 · 91 citations

Pharmacy, Medicinal Chemistry, Drug Discovery +6