Abl tyrosine kinases are required for infection by Shigella flexneri

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

Brian Druker, Charles L. Sawyers, Hagop M. Kantarjian et al. · New England Journal of Medicine · 2001 · 2.7K citations · Full text

Medicine, Hematology, Oncology +17

Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase

Bhushan Nagar, Oliver Hantschel, Matthew A. Young et al. · Cell · 2003 · 877 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow

Warren S. Pear, Juli P. Miller, Lanwei Xu et al. · Blood · 1998 · 738 citations

Medicine, Hematology, Oncology +12

PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

Phillip T. Hawkins, A. Eguinoa, Rongguo Qiu et al. · Current Biology · 1995 · 541 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

The Tripartite Type III Secreton of <i>Shigella flexneri</i> Inserts Ipab and Ipac into Host Membranes

Ariel Blocker, Pierre Gounon, Éric Larquet et al. · The Journal of Cell Biology · 1999 · 492 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17