Concepedia

Novel antinematodal and antiparasitic agents from Penicillium charlesii. I. Fermentation, isolation and biological activity.

John G. Ondeyka, Robert T. Goegelman, James M. Schaeffer, L. Kelemen, LAURETTA ZITANO

The Journal of Antibiotics · 1990 · 118 citations · 10 references

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Abstract

Paraherquamide and six novel analogs were isolated from the fermentation of Penicillium charlesii (ATCC 20841). All seven natural products displayed potent antinematodal activity against Caenorhabditis elegans. None of the novel analogs were more potent than paraherquamide.

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Isolation and structure (X-ray analysis) of marcfortine A, a new alkaloid from Penicillium roqueforti

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Novel antinematodal and antiparasitic agents from Penicillium charlesii. II. Structure determination of paraherquamides B, C, D, E, F, and G.

Jerrold M. Liesch, C. F. WICHMANN · The Journal of Antibiotics · 1990 · 112 citations · Full text

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