Jerrold M. Liesch

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

Daniel M. Bollag, Patricia A. McQueney, Jian‐Yong Zhu et al. · PubMed · 1995 · 686 citations

Medicine, Medicinal Chemistry, Pharmacology +15

A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus

Ray Chang, Virginia Lotti, Richard L. Monaghan et al. · Science · 1985 · 320 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Pharmaceuticals from cultured algae

Robert E. Schwartz, C. F. Hirsch, David F. Sesin et al. · Journal of Industrial Microbiology & Biotechnology · 1990 · 313 citations · Full text

Life Sciences, Biotechnology, Marine Biotechnology +9

Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya.

M Sanada, Tetsuji Miyano, Shuichi Iwadare et al. · The Journal of Antibiotics · 1986 · 164 citations · Full text

Life Sciences, Biotechnology, Microbiology +13