Development and Validation of a Preclinical Food Effect Model

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

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Pharmacokinetics of Celecoxib after Oral Administration in Dogs and Humans: Effect of Food and Site of Absorption

Susan K. Paulson, Margaret B. Vaughn, Susan M. Jessen et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 286 citations

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The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human

Yunhui Wu, Alice E. Loper, Elizabeth Landis et al. · International Journal of Pharmaceutics · 2004 · 272 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Biorelevant Dissolution Testing to Predict the Plasma Profile of Lipophilic Drugs After Oral Administration

Eleftheria Nicolaides, Moira Symillides, Jennifer Dressman et al. · Pharmaceutical Research · 2001 · 208 citations

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Comparison of Gastrointestinal pH in Dogs and Humans: Implications on the Use of the Beagle Dog as a Model for Oral Absorption in Humans

Chung Y. Lui, Gordon L. Amidon, Rosemary R. Berardi et al. · Journal of Pharmaceutical Sciences · 1986 · 199 citations

Pharmacy, Pharmacokinetics, Veterinary Physiology +16