Concepedia

Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect

Angela Calastretti, Francesca Rancati, Michela Ceriani, Laura Asnaghi, Gianfranco Canti, A Nicolin

European Journal of Cancer · 2001 · 42 citations · 33 references

DOI

Concepts

References

33

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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Cancer: Principles and Practice of Oncology.

Annals of Internal Medicine · 1991 · 8.5K citations

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Ildo Nicoletti, Graziella Migliorati, Maria Cristina Pagliacci et al. · Journal of Immunological Methods · 1991 · 4.6K citations

, , +7

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

, , +13

A mammalian protein targeted by G1-arresting rapamycin–receptor complex

Eric J. Brown, Mark W. Albers, Tae Bum Shin et al. · Nature · 1994 · 2.1K citations

, , +11