Concepedia

V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals

David B. Roth, Pamela B. Nakajima, Joseph P. Menetski, Melvin J. Bosma, Martin Gellert

Cell · 1992 · 187 citations · 59 references

Concepts

Life SciencesGeneticsImmunologyCellular ImmunologyDna RepairRecombinationAntigen Receptor Gene RearrangementT Cell BiologyT Cell DevelopmentT-cell Receptor GeneticsThymic DevelopmentV(d)j RecombinationDna Double-strand BreaksDouble-strand Dna BreaksT Cell Receptor RearrangementT-cell Receptor Locus RearrangementThymic T-cell Receptor Gene RearrangementV(d)j Recombination DefectsV(d)j Recombination Mechanism

References

59

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Andrew P. Feinberg, Bert Vogelstein · Analytical Biochemistry · 1983 · 25.2K citations

Life Sciences, Genetics, Molecular Biology +7

Somatic generation of antibody diversity

Susumu Tonegawa · Nature · 1983 · 4K citations

Life Sciences, Biotechnology, Immunology +14

Somatic generation of antibody diversity.

PubMed · 1976 · 3.3K citations

Life Sciences, Biotechnology, Immunology +14

A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

The V(D)J recombination activating gene, RAG-1

David G. Schatz, Marjorie A. Oettinger, David Baltimore · Cell · 1989 · 1.2K citations · Full text

Medicine, Genetics, Molecular Genetics +11