Concepedia

ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells

Yong Zhang, Guoyu Yu, Dongmei Wang, Ying Hu, Weiwei Lei

Toxicon · 2011 · 13 citations · 17 references

DOI

Concepts

References

17

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Alessandro Vannini, Cinzia Volpari, Gessica Filocamo et al. · Proceedings of the National Academy of Sciences · 2004 · 627 citations · Full text

, , +13

Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

Andrew J. Wilson, Do-Sun Byun, Lucas B. Murray et al. · Journal of Biological Chemistry · 2006 · 581 citations · Full text

, , +17

Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals.

Bryan A. Ballif, John Blenis · PubMed · 2001 · 425 citations

, , +16

Cell fate decisions are specified by the dynamic ERK interactome

Alex von Kriegsheim, Daniela Baiocchi, Marc R. Birtwistle et al. · Nature Cell Biology · 2009 · 293 citations

, , +14

Carboplatin and Paclitaxel in Combination With Either Vorinostat or Placebo for First-Line Therapy of Advanced Non–Small-Cell Lung Cancer

Suresh S. Ramalingam, Michael L. Maitland, Paul Frankel et al. · Journal of Clinical Oncology · 2009 · 270 citations

, , +16