The novel calpain inhibitor A-705253 prevents stress-induced tau hyperphosphorylation in vitro and in vivo

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolić et al. · Nature · 1999 · 1.5K citations

Life Sciences, Molecular Genetics, Neuroscience +10

Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease

Masashi Kitazawa, Salvatore Oddo, Tritia R. Yamasaki et al. · Journal of Neuroscience · 2005 · 689 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia

Emmanuel Planel, K. Richter, Charles E. Nolan et al. · Journal of Neuroscience · 2007 · 390 citations · Full text

Life Sciences, Anesthesiology, Neuroscience +13

Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice

Jin G. Sheng · Neurobiology of Disease · 2003 · 386 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17