Concepedia

Pyrrolo[3,2,1- ij ]quinoline derivatives, a 5-HT 2c receptor agonist with selectivity over the 5-HT 2a receptor: potential therapeutic applications for epilepsy and obesity

Methvin Isaac, Abdelmalik Slassi, Anne O’Brien, Louise Edwards, Neil MacLean, Donna Bueschkens, David K.H. Lee, Kirk McCallum, Inés de Lannoy, Lidia Demchyshyn,

Bioorganic & Medicinal Chemistry Letters · 2000 · 40 citations · 7 references

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7

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Laurence H. Tecott, Linda M. Sun, Susan F. Akana et al. · Nature · 1995 · 1.3K citations

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Comparative localization of serotonin<sub>1A, 1C</sub>, and <sub>2</sub> receptor subtype mRNAs in rat brain

Douglas E. Wright, Kim B. Seroogy, Kerstin H. Lundgren et al. · The Journal of Comparative Neurology · 1995 · 546 citations

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Serotonin activates the mitogen-activated protein kinase pathway in vascular smooth muscle: use of the mitogen-activated protein kinase kinase inhibitor PD098059.

Stephanie W. Watts · Journal of Pharmacology and Experimental Therapeutics · 1996 · 121 citations

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Novel Agonists of 5HT<sub>2C</sub> Receptors. Synthesis and Biological Evaluation of Substituted 2-(Indol-1-yl)-1-methylethylamines and 2-(Indeno[1,2-<i>b</i>]pyrrol-1-yl)-1-methylethylamines. Improved Therapeutics for Obsessive Compulsive Disorder

Michael Bös, François Jenck, James R. Martin et al. · Journal of Medicinal Chemistry · 1997 · 97 citations · Full text

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Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annulated indole derivatives. 1

I. van Wijngaarden, D. Hamminga, Rolf van Hes et al. · Journal of Medicinal Chemistry · 1993 · 74 citations · Full text

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