Louise Edwards

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 166 citations · Full text

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3<i>H</i>]indol]-2′(1′<i>H</i>)-ones as Orally Bioavailable Antitumor Agents

Peter B. Sampson, Yong Liu, Narendra Kumar Patel et al. · Journal of Medicinal Chemistry · 2014 · 109 citations

Pharmaceutical Science, Polo-like Kinase Family, Compound 18 +22

Pyrrole chemistry. XXVIII. Substitution reactions of 1-(phenylsulfonyl)pyrrole and some derivatives

Hugh J. Anderson, Charles E. Loader, Ru Xun Xu et al. · Canadian Journal of Chemistry · 1985 · 103 citations · Full text

Derivative (Chemistry), Derivatives, Engineering +12

Cobalt-Catalyzed [2.pi. + 2.pi. + 2.pi.] (Homo-Diels-Alder) and [2.pi. + 2.pi. + 4.pi.] Cycloadditions of Bicyclo[2.2.1]hepta-2,5-dienes

Mark Lautens, William Tam, Julia Craig Lautens et al. · Journal of the American Chemical Society · 1995 · 95 citations

Chemical Engineering, Engineering, Heterocyclic +9

The Discovery of PLK4 Inhibitors: (<i>E</i>)-3-((1<i>H</i>-Indazol-6-yl)methylene)indolin-2-ones as Novel Antiproliferative Agents

Radoslaw S. Laufer, Bryan Forrest, Sze-Wan Li et al. · Journal of Medicinal Chemistry · 2013 · 71 citations · Full text

Molecular Biology, Pharmacotherapy, Chemical Biology +18